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Mutations of KRAS, NRAS, BRAF, EGFR, and PIK3CA genes in urachal carcinoma: Occurence and prognostic significance
PURPOSE: Targeted therapy represents an attractive alternative for rare tumors such as urachal carcinoma (UrC). The aim of this study was to assess the mutations of the most commonly affected 5 genes in the targetable EGFR-pathway in UrC and comapre their frequencies to those of found in urothelial...
Autores principales: | Módos, Orsolya, Reis, Henning, Niedworok, Christian, Rübben, Herbert, Szendröi, Attila, Marcell A., Szász, Tímár, József, Baghy, Kornélia, Kovalszky, Ilona, Golabek, Tomasz, Chlosta, Piotr, Okon, Krzysztof, Peyronnet, Benoit, Mathieu, Romain, Shariat, Shahrokh F., Hollósi, Péter, Nyirády, Péter, Szarvas, Tibor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129933/ https://www.ncbi.nlm.nih.gov/pubmed/27283768 http://dx.doi.org/10.18632/oncotarget.9828 |
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