Modulation of macrophage polarization and lung cancer cell stemness by MUC1 and development of a related small-molecule inhibitor pterostilbene

Tumor-associated macrophages (TAMs) polarized to the M2 phenotype play key roles in tumor progression in different cancer types, including lung cancer. MUC1 expression in various types of cancer is an indicator of poorer prognosis. Elevated MUC1 expression has been reported in inflammatory lung macr...

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Detalles Bibliográficos
Autores principales: Huang, Wen-Chien, Chan, Mei-Lin, Chen, Ming-Jen, Tsai, Tung-Hu, Chen, Yu-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129938/
https://www.ncbi.nlm.nih.gov/pubmed/27276704
http://dx.doi.org/10.18632/oncotarget.8101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129938/
https://www.ncbi.nlm.nih.gov/pubmed/27276704
http://dx.doi.org/10.18632/oncotarget.8101

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