The chronological sequence of somatic mutations in early gastric carcinogenesis inferred from multiregion sequencing of gastric adenomas

Mutation profiles and intratumoral heterogeneity are not well understood for benign gastric adenomas, some of which progress into malignant gastric adenocarcinomas. In this study, we performed whole-exome sequencing of three microsatellite stable (MSS) and two microsatellite instability-high (MSI-H)...

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Detalles Bibliográficos
Autores principales: Lim, Chul-Hyun, Cho, Yu Kyung, Kim, Sang Woo, Choi, Myung-Gyu, Rhee, Je-Keun, Chung, Yeun-Jun, Lee, Sug-Hyung, Kim, Tae-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129968/
https://www.ncbi.nlm.nih.gov/pubmed/27175599
http://dx.doi.org/10.18632/oncotarget.9250

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