Tumor-selective replication herpes simplex virus-based technology significantly improves clinical detection and prognostication of viable circulating tumor cells

Detection of circulating tumor cells remains a significant challenge due to their vast physical and biological heterogeneity. We developed a cell-surface-marker-independent technology based on telomerase-specific, replication-selective oncolytic herpes-simplex-virus-1 that targets telomerase-reverse...

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Detalles Bibliográficos
Autores principales: Zhang, Wen, Bao, Li, Yang, Shaoxing, Qian, Zhaoyang, Dong, Mei, Yin, Liyuan, Zhao, Qian, Ge, Keli, Deng, Zhenling, Zhang, Jing, Qi, Fei, An, Zhongxue, Yu, Yuan, Wang, Qingbo, Wu, Renhua, Fan, Fan, Zhang, Lianfeng, Chen, Xiping, Na, Yingjian, Feng, Lin, liu, Lingling, Zhu, Yujie, Qin, Tiancheng, Zhang, Shuren, Zhang, Youhui, Zhang, Xiuqing, Wang, Jian, Yi, Xin, Zou, Liqun, Xin, Hong-Wu, Ditzel, Henrik J., Gao, Hongjun, Zhang, Kaitai, Liu, Binlei, Cheng, Shujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129969/
https://www.ncbi.nlm.nih.gov/pubmed/27206795
http://dx.doi.org/10.18632/oncotarget.9465

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