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Indolin-2-one compounds targeting thioredoxin reductase as potential anticancer drug leads

Several compounds bearing the indolinone chemical scaffold are known to possess anticancer properties. For example, the tyrosine kinase inhibitor sunitinib is an arylideneindolin-2-one compound. The chemical versatility associated with structural modifications of indolinone compounds underlies the p...

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Detalles Bibliográficos
Autores principales:	Kaminska, Kamila K., Bertrand, Helene C., Tajima, Hisashi, Stafford, William C., Cheng, Qing, Chen, Wan, Wells, Geoffrey, Arner, Elias S.J., Chew, Eng-Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130005/ https://www.ncbi.nlm.nih.gov/pubmed/27244886 http://dx.doi.org/10.18632/oncotarget.9579

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