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A new antiproliferative noscapine analogue: chemical synthesis and biological evaluation

Noscapine, a naturally occurring opium alkaloid, is a widely used antitussive medication. Noscapine has low toxicity and recently it was also found to possess cytotoxic activity which led to the development of many noscapine analogues. In this paper we report on the synthesis and testing of a novel...

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Detalles Bibliográficos
Autores principales: Ghaly, Peter E., Abou El-Magd, Rabab M., Churchill, Cassandra D. M., Tuszynski, Jack A., West, F. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130025/
https://www.ncbi.nlm.nih.gov/pubmed/27777381
http://dx.doi.org/10.18632/oncotarget.9642