Reduced CD146 expression promotes tumorigenesis and cancer stemness in colorectal cancer through activating Wnt/β-catenin signaling

Cancer stemness drives tumor progression and drug resistance, representing a challenge to cancer eradication. Compelling evidence indicates that cancer cells can reenter the stem cell state due to the reprogramming of self-renewal machinery. Here, we show that CD146 knockdown induces stem cell prope...

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Detalles Bibliográficos
Autores principales: Liu, Dan, Du, Lei, Chen, Dong, Ye, Zhongde, Duan, Hongxia, Tu, Tao, Feng, Jing, Yang, Yili, Chen, Quan, Yan, Xiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130037/
https://www.ncbi.nlm.nih.gov/pubmed/27302922
http://dx.doi.org/10.18632/oncotarget.9930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130037/
https://www.ncbi.nlm.nih.gov/pubmed/27302922
http://dx.doi.org/10.18632/oncotarget.9930

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