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Repurposing metformin for cancer treatment: current clinical studies
In recent years, several studies have presented evidence suggesting a potential role for metformin in anti-cancer therapy. Preclinical studies have demonstrated several anticancer molecular mechanisms of metformin including mTOR inhibition, cytotoxic effects, and immunomodulation. Epidemiologic data...
Autores principales: | Chae, Young Kwang, Arya, Ayush, Malecek, Mary-Kate, Shin, Daniel Sanghoon, Carneiro, Benedito, Chandra, Sunandana, Kaplan, Jason, Kalyan, Aparna, Altman, Jessica K., Platanias, Leonidas, Giles, Francis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130043/ https://www.ncbi.nlm.nih.gov/pubmed/27004404 http://dx.doi.org/10.18632/oncotarget.8194 |
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