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The emerging roles and therapeutic potential of cyclin-dependent kinase 11 (CDK11) in human cancer

Overexpression and/or hyperactivation of cyclin-dependent kinases (CDKs) are common features of most cancer types. CDKs have been shown to play important roles in tumor cell proliferation and growth by controlling cell cycle, transcription, and RNA splicing. CDK4/6 inhibitor palbociclib has been rec...

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Detalles Bibliográficos
Autores principales: Zhou, Yubing, Shen, Jacson K., Hornicek, Francis J., Kan, Quancheng, Duan, Zhenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130049/
https://www.ncbi.nlm.nih.gov/pubmed/27049727
http://dx.doi.org/10.18632/oncotarget.8519