Methylation of Breast Cancer Predisposition Genes in Early-Onset Breast Cancer: Australian Breast Cancer Family Registry

DNA methylation can mimic the effects of both germline and somatic mutations for cancer predisposition genes such as BRCA1 and p16(INK4a). Constitutional DNA methylation of the BRCA1 promoter has been well described and is associated with an increased risk of early-onset breast cancers that have BRC...

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Detalles Bibliográficos
Autores principales: Scott, Cameron M., Joo, JiHoon Eric, O’Callaghan, Neil, Buchanan, Daniel D., Clendenning, Mark, Giles, Graham G., Hopper, John L., Wong, Ee Ming, Southey, Melissa C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130174/
https://www.ncbi.nlm.nih.gov/pubmed/27902704
http://dx.doi.org/10.1371/journal.pone.0165436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130174/
https://www.ncbi.nlm.nih.gov/pubmed/27902704
http://dx.doi.org/10.1371/journal.pone.0165436

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