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Role of Hepatic-Specific Transcription Factors and Polycomb Repressive Complex 2 during Induction of Fibroblasts to Hepatic Fate

Direct reprogramming using defined sets of transcription factors (TFs) is a recent strategy for generating induced hepatocytes (iHeps) from fibroblasts for use in regenerative medicine and drug development. Comprehensive studies detailing the regulatory role of TFs during this reprogramming process...

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Detalles Bibliográficos
Autores principales: Rastegar-Pouyani, Shima, Khazaei, Niusha, Wee, Ping, Mohammadnia, Abdulshakour, Yaqubi, Moein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130264/
https://www.ncbi.nlm.nih.gov/pubmed/27902735
http://dx.doi.org/10.1371/journal.pone.0167081