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Exploration of a Polygenic Risk Score for Alcohol Consumption: A Longitudinal Analysis from the ALSPAC Cohort

BACKGROUND: Uncertainty remains about the true extent by which alcohol consumption causes a number of health outcomes. Genetic variants, or combinations of variants built into a polygenic risk score (PGRS), can be used in an instrumental variable framework to assess causality between a phenotype and...

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Detalles Bibliográficos
Autores principales:	Taylor, Michelle, Simpkin, Andrew J., Haycock, Philip C., Dudbridge, Frank, Zuccolo, Luisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130278/ https://www.ncbi.nlm.nih.gov/pubmed/27902751 http://dx.doi.org/10.1371/journal.pone.0167360

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