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DNA cytosine hydroxymethylation levels are distinct among non-overlapping classes of peripheral blood leukocytes

BACKGROUND: Peripheral blood leukocytes are the most commonly used surrogates to study epigenome-induced risk and epigenomic response to disease-related stress. We considered the hypothesis that the various classes of peripheral leukocytes differentially regulate the synthesis of 5-methylcytosine (5...

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Detalles Bibliográficos
Autores principales: Hohos, Natalie M., Lee, Kevin, Ji, Lexiang, Yu, Miao, Kandasamy, Muthugapatti M., Phillips, Bradley G., Baile, Clifton A., He, Chuan, Schmitz, Robert J., Meagher, Richard B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131182/
https://www.ncbi.nlm.nih.gov/pubmed/27164004
http://dx.doi.org/10.1016/j.jim.2016.05.003

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