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Multi-phase post-mortem CT-angiography: a pathologic correlation study on cardiovascular sudden death
Multi-phase post-mortem CT-angiography (MPMCTA) has the great potential to increase the quality of the post-mortem investigation, especially in the area of sudden death; however, its role as routine complement to the pathology toolbox is still questioned as it needs to be further standardized. The a...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Science Press
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131201/ https://www.ncbi.nlm.nih.gov/pubmed/27928228 http://dx.doi.org/10.11909/j.issn.1671-5411.2016.10.003 |
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author | Turillazzi, Emanuela Frati, Paola Pascale, Natascha Pomara, Cristoforo Grilli, Giampaolo Viola, Rocco Valerio Fineschi, Vittorio |
author_facet | Turillazzi, Emanuela Frati, Paola Pascale, Natascha Pomara, Cristoforo Grilli, Giampaolo Viola, Rocco Valerio Fineschi, Vittorio |
author_sort | Turillazzi, Emanuela |
collection | PubMed |
description | Multi-phase post-mortem CT-angiography (MPMCTA) has the great potential to increase the quality of the post-mortem investigation, especially in the area of sudden death; however, its role as routine complement to the pathology toolbox is still questioned as it needs to be further standardized. The aim of this study is to investigate the contribution of MPMCTA in cases of sudden unexplained death in adults and in particular in sudden cardiovascular death. Sixty-eight sudden unexpected deaths of adults were investigated at our institution between 2012 and 2013. Ten cases underwent MPMCTA and autopsy and were included in the study. Before the angiographic step by complete filling of the vascular system, prior to any manipulation of the body, a non-contrast CT-scan was carried out. Image reconstructions were performed on a CT workstation (Vitrea) and two radiologists experienced with post mortem imaging interpreted the MPMCTA findings. In all 10 cases, we could state a good correlation between combination of post-mortem CT and MPMCTA and autopsy procedures, confirming a high diagnostic sensitivity. With this case series we want to illustrate the advantages offered by performing MPMCTA when facing a sudden death, regardless of specific suspicion for acute coronary syndrome or other vascular or ischemic disease. |
format | Online Article Text |
id | pubmed-5131201 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Science Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-51312012016-12-07 Multi-phase post-mortem CT-angiography: a pathologic correlation study on cardiovascular sudden death Turillazzi, Emanuela Frati, Paola Pascale, Natascha Pomara, Cristoforo Grilli, Giampaolo Viola, Rocco Valerio Fineschi, Vittorio J Geriatr Cardiol Case Report Multi-phase post-mortem CT-angiography (MPMCTA) has the great potential to increase the quality of the post-mortem investigation, especially in the area of sudden death; however, its role as routine complement to the pathology toolbox is still questioned as it needs to be further standardized. The aim of this study is to investigate the contribution of MPMCTA in cases of sudden unexplained death in adults and in particular in sudden cardiovascular death. Sixty-eight sudden unexpected deaths of adults were investigated at our institution between 2012 and 2013. Ten cases underwent MPMCTA and autopsy and were included in the study. Before the angiographic step by complete filling of the vascular system, prior to any manipulation of the body, a non-contrast CT-scan was carried out. Image reconstructions were performed on a CT workstation (Vitrea) and two radiologists experienced with post mortem imaging interpreted the MPMCTA findings. In all 10 cases, we could state a good correlation between combination of post-mortem CT and MPMCTA and autopsy procedures, confirming a high diagnostic sensitivity. With this case series we want to illustrate the advantages offered by performing MPMCTA when facing a sudden death, regardless of specific suspicion for acute coronary syndrome or other vascular or ischemic disease. Science Press 2016-10 /pmc/articles/PMC5131201/ /pubmed/27928228 http://dx.doi.org/10.11909/j.issn.1671-5411.2016.10.003 Text en Institute of Geriatric Cardiology http://creativecommons.org/licenses/by-nc-sa/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License, which allows readers to alter, transform, or build upon the article and then distribute the resulting work under the same or similar license to this one. The work must be attributed back to the original author and commercial use is not permitted without specific permission. |
spellingShingle | Case Report Turillazzi, Emanuela Frati, Paola Pascale, Natascha Pomara, Cristoforo Grilli, Giampaolo Viola, Rocco Valerio Fineschi, Vittorio Multi-phase post-mortem CT-angiography: a pathologic correlation study on cardiovascular sudden death |
title | Multi-phase post-mortem CT-angiography: a pathologic correlation study on cardiovascular sudden death |
title_full | Multi-phase post-mortem CT-angiography: a pathologic correlation study on cardiovascular sudden death |
title_fullStr | Multi-phase post-mortem CT-angiography: a pathologic correlation study on cardiovascular sudden death |
title_full_unstemmed | Multi-phase post-mortem CT-angiography: a pathologic correlation study on cardiovascular sudden death |
title_short | Multi-phase post-mortem CT-angiography: a pathologic correlation study on cardiovascular sudden death |
title_sort | multi-phase post-mortem ct-angiography: a pathologic correlation study on cardiovascular sudden death |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131201/ https://www.ncbi.nlm.nih.gov/pubmed/27928228 http://dx.doi.org/10.11909/j.issn.1671-5411.2016.10.003 |
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