Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface

The mechanism by which the HIV-1 MPER epitope is recognized by the potent neutralizing antibody 10E8 at membrane interfaces remains poorly understood. To solve this problem, we have optimized a 10E8 peptide epitope and analyzed the structure and binding activities of the antibody in membrane and mem...

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Detalles Bibliográficos
Autores principales: Rujas, Edurne, Caaveiro, Jose M. M., Partida-Hanon, Angélica, Gulzar, Naveed, Morante, Koldo, Apellániz, Beatriz, García-Porras, Miguel, Bruix, Marta, Tsumoto, Kouhei, Scott, Jamie K., Jiménez, M. Ángeles, Nieva, José L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131266/
https://www.ncbi.nlm.nih.gov/pubmed/27905530
http://dx.doi.org/10.1038/srep38177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131266/
https://www.ncbi.nlm.nih.gov/pubmed/27905530
http://dx.doi.org/10.1038/srep38177

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