Cargando…

Anti-Hu antibodies activate enteric and sensory neurons

IgG of type 1 anti-neuronal nuclear antibody (ANNA-1, anti-Hu) specificity is a serological marker of paraneoplastic neurological autoimmunity (including enteric/autonomic) usually related to small-cell lung carcinoma. We show here that IgG isolated from such sera and also affinity-purified anti-HuD...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Qin, Michel, Klaus, Annahazi, Anita, Demir, Ihsan E., Ceyhan, Güralp O., Zeller, Florian, Komorowski, Lars, Stöcker, Winfried, Beyak, Michael J., Grundy, David, Farrugia, Gianrico, De Giorgio, Roberto, Schemann, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131267/ https://www.ncbi.nlm.nih.gov/pubmed/27905561 http://dx.doi.org/10.1038/srep38216

Ejemplares similares

Activity of Protease-Activated Receptors in Primary Cultured Human Myenteric Neurons
por: Kugler, Eva M., et al.
Publicado: (2012)

Mechanical stress activates neurites and somata of myenteric neurons
por: Kugler, Eva M., et al.
Publicado: (2015)

Calcium Imaging of Nerve-Mast Cell Signaling in the Human Intestine
por: Buhner, Sabine, et al.
Publicado: (2017)

Enteric neuroanatomy and smooth muscle activity in the western diamondback rattlesnake (Crotalus atrox)
por: Kohl, Tobias, et al.
Publicado: (2023)

Nerve-Cancer Interactions in the Stromal Biology of Pancreatic Cancer
por: Demir, Ihsan Ekin, et al.
Publicado: (2012)

Surgery and the kings of medical science: Invited Commentary: “Publication activity of chief and senior general/visceral surgeons in German university hospitals — a ten-year analysis”, Böckmann et al.
por: Demir, Ihsan Ekin, et al.
Publicado: (2021)

Back pain as a potential indicator of local recurrence in pancreatic cancer
por: Tieftrunk, Elke, et al.
Publicado: (2015)

Continuous irrigation after pancreatectomy: a systematic review
por: Pergolini, Ilaria, et al.
Publicado: (2023)

Distension evoked mucosal secretion in human and porcine colon in vitro
por: Elfers, Kristin, et al.
Publicado: (2023)

Protease signaling through protease activated receptor 1 mediate nerve activation by mucosal supernatants from irritable bowel syndrome but not from ulcerative colitis patients
por: Buhner, Sabine, et al.
Publicado: (2018)

Pain mechanisms in chronic pancreatitis: of a master and his fire
por: Demir, Ihsan Ekin, et al.
Publicado: (2010)

Neural Invasion in Pancreatic Cancer: The Past, Present and Future
por: Demir, Ihsan Ekin, et al.
Publicado: (2010)

Compression and stretch sensitive submucosal neurons of the porcine and human colon
por: Filzmayer, Anna Katharina, et al.
Publicado: (2020)

Mechanosensitivity in the enteric nervous system
por: Mazzuoli-Weber, Gemma, et al.
Publicado: (2015)

Mechanosensitive Enteric Neurons in the Myenteric Plexus of the Mouse Intestine
por: Mazzuoli, Gemma, et al.
Publicado: (2012)

Insulin/IGF-driven cancer cell-stroma crosstalk as a novel therapeutic target in pancreatic cancer
por: Mutgan, Ayse Ceren, et al.
Publicado: (2018)

Mechanosensitive enteric neurons in the guinea pig gastric corpus
por: Mazzuoli-Weber, Gemma, et al.
Publicado: (2015)

Pancreatic stump closure techniques and pancreatic fistula formation after distal pancreatectomy: Meta-analysis and single-center experience
por: Tieftrunk, Elke, et al.
Publicado: (2018)

Organoids to Study Intestinal Nutrient Transport, Drug Uptake and Metabolism – Update to the Human Model and Expansion of Applications
por: Zietek, Tamara, et al.
Publicado: (2020)

Towards a neurobiological understanding of pain in chronic pancreatitis: mechanisms and implications for treatment
por: Olesen, Søren S., et al.
Publicado: (2017)

Perineural Mast Cells Are Specifically Enriched in Pancreatic Neuritis and Neuropathic Pain in Pancreatic Cancer and Chronic Pancreatitis
por: Demir, Ihsan Ekin, et al.
Publicado: (2013)

Mechanisms of T-Cell Exhaustion in Pancreatic Cancer
por: Saka, Didem, et al.
Publicado: (2020)

Changes in the gastric enteric nervous system and muscle: A case report on two patients with diabetic gastroparesis
por: Pasricha, Pankaj J, et al.
Publicado: (2008)

Optimal Endpoint of Therapy in IBD: An Update on Factors Determining a Successful Drug Withdrawal
por: Annaházi, Anita, et al.
Publicado: (2015)

Perineural invasion in pancreatic cancer: proteomic analysis and in vitro modelling
por: Alrawashdeh, Wasfi, et al.
Publicado: (2019)

Targeting the undruggable oncogenic KRAS: the dawn of hope
por: Asimgil, Hande, et al.
Publicado: (2022)

Targeting nNOS ameliorates the severe neuropathic pain due to chronic pancreatitis
por: Demir, Ihsan Ekin, et al.
Publicado: (2019)

The impact of MFG-E8 in chronic pancreatitis: potential for future immunotherapy?
por: D’Haese, Jan G, et al.
Publicado: (2013)

Patterns and Relevance of Langerhans Islet Invasion in Pancreatic Cancer
por: Goess, Ruediger, et al.
Publicado: (2021)

Innervated mouse pancreas organoids as an ex vivo model to study pancreatic neuropathy in pancreatic cancer
por: Besikcioglu, H. Erdinc, et al.
Publicado: (2021)

Arterial Resection for Pancreatic Cancer: Feasibility and Current Standing in a High-Volume Center
por: Ren, Lei, et al.
Publicado: (2023)

Bacterial content of the human pancreatic duct: An observational study
por: Demir, Elke, et al.
Publicado: (2022)

Innovation Lessons From the COVID-19 Pandemic
por: Farrugia, Gianrico, et al.
Publicado: (2020)

Indirect cholinergic activation slows down pancreatic cancer growth and tumor-associated inflammation
por: Pfitzinger, Paulo L., et al.
Publicado: (2020)

FLUID PHASE DESTRUCTION OF C2(hu) BY C1(hu) : II. UNMASKING BY C4i(hu)OF C1(hu) SPECIFICITY FOR C2(hu)
por: Gigli, Irma, et al.
Publicado: (1969)

HuB and HuD repress telomerase activity by dissociating HuR from TERC
por: Cheng, Xiaolei, et al.
Publicado: (2021)

Think big, start small, move fast: a blueprint for transformation from the Mayo Clinic Center for Innovation
por: LaRusso, Nicholas, et al.
Publicado: (2015)

The Mast Cell Degranulator Compound 48/80 Directly Activates Neurons
por: Schemann, Michael, et al.
Publicado: (2012)

Reduced nuclear export of HuR mRNA by HuR is linked to the loss of HuR in replicative senescence
por: Yi, Jie, et al.
Publicado: (2010)

Downregulation of P2Y2 and HuD during the development of the enteric nervous system in fetal rats with anorectal malformations
por: Zheng, Zebing, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_qs4e712rnluoqoeds5pjcb6r75