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Shikonin induces mitochondria-mediated apoptosis and enhances chemotherapeutic sensitivity of gastric cancer through reactive oxygen species

The prognosis of gastric cancer remains poor due to clinical drug resistance. Novel drugs are urgently needed. Shikonin (SHK), a natural naphthoquinone, has been reported to trigger cell death and overcome drug resistance in anti-tumour therapy. In this study, we investigated the effectiveness and m...

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Detalles Bibliográficos
Autores principales:	Liang, Wenquan, Cai, Aizhen, Chen, Guozhu, Xi, Hongqing, Wu, Xiaosong, Cui, Jianxin, Zhang, Kecheng, Zhao, Xudong, Yu, Jiyun, Wei, Bo, Chen, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131274/ https://www.ncbi.nlm.nih.gov/pubmed/27905569 http://dx.doi.org/10.1038/srep38267

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