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Inter-laboratory evolution of a model organism and its epistatic effects on mutagenesis screens
In theory, a few naturally occurring evolutionary changes in the genome of a model organism may have little or no observable impact on its wild type phenotype, and yet still substantially impact the phenotypes of mutant strains through epistasis. To see if this is happening in a model organism, we o...
Autores principales: | Bradley, Michael D., Neu, Devin, Bahar, Fatmagul, Welch, Roy D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131308/ https://www.ncbi.nlm.nih.gov/pubmed/27905490 http://dx.doi.org/10.1038/srep38001 |
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