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Inter-laboratory evolution of a model organism and its epistatic effects on mutagenesis screens

In theory, a few naturally occurring evolutionary changes in the genome of a model organism may have little or no observable impact on its wild type phenotype, and yet still substantially impact the phenotypes of mutant strains through epistasis. To see if this is happening in a model organism, we o...

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Detalles Bibliográficos
Autores principales: Bradley, Michael D., Neu, Devin, Bahar, Fatmagul, Welch, Roy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131308/
https://www.ncbi.nlm.nih.gov/pubmed/27905490
http://dx.doi.org/10.1038/srep38001

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