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Cellular aspartyl proteases promote the unconventional secretion of biologically active HIV-1 matrix protein p17

The human immune deficiency virus type 1 (HIV-1) matrix protein p17 (p17), although devoid of a signal sequence, is released by infected cells and detected in blood and in different organs and tissues even in HIV-1-infected patients undergoing successful combined antiretroviral therapy (cART). Extra...

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Detalles Bibliográficos
Autores principales: Caccuri, Francesca, Iaria, Maria Luisa, Campilongo, Federica, Varney, Kristen, Rossi, Alessandro, Mitola, Stefania, Schiarea, Silvia, Bugatti, Antonella, Mazzuca, Pietro, Giagulli, Cinzia, Fiorentini, Simona, Lu, Wuyuan, Salmona, Mario, Caruso, Arnaldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131311/
https://www.ncbi.nlm.nih.gov/pubmed/27905556
http://dx.doi.org/10.1038/srep38027