Mixed acid-base disorder secondary to topiramate use in traumatic brain injury

We report a case of a man with traumatic brain injury. He was started on to prophylactic topiramate which led to a mixed acid-base disorder. He had severe metabolic acidosis secondary to renal tubular acidification defect and respiratory alkalosis secondary to hyperventilation. Withdrawal of the off...

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Detalles Bibliográficos
Autores principales: Golla, S., Anandh, U., Balasubramaniam, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131386/
https://www.ncbi.nlm.nih.gov/pubmed/27942179
http://dx.doi.org/10.4103/0971-4065.177136
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author Golla, S.
Anandh, U.
Balasubramaniam, A.
author_facet Golla, S.
Anandh, U.
Balasubramaniam, A.
author_sort Golla, S.
collection PubMed
description We report a case of a man with traumatic brain injury. He was started on to prophylactic topiramate which led to a mixed acid-base disorder. He had severe metabolic acidosis secondary to renal tubular acidification defect and respiratory alkalosis secondary to hyperventilation. Withdrawal of the offending drug led to the prompt resolution of the acid-base disturbance.
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spelling pubmed-51313862016-12-09 Mixed acid-base disorder secondary to topiramate use in traumatic brain injury Golla, S. Anandh, U. Balasubramaniam, A. Indian J Nephrol Case Report We report a case of a man with traumatic brain injury. He was started on to prophylactic topiramate which led to a mixed acid-base disorder. He had severe metabolic acidosis secondary to renal tubular acidification defect and respiratory alkalosis secondary to hyperventilation. Withdrawal of the offending drug led to the prompt resolution of the acid-base disturbance. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC5131386/ /pubmed/27942179 http://dx.doi.org/10.4103/0971-4065.177136 Text en Copyright: © Indian Journal of Nephrology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Golla, S.
Anandh, U.
Balasubramaniam, A.
Mixed acid-base disorder secondary to topiramate use in traumatic brain injury
title Mixed acid-base disorder secondary to topiramate use in traumatic brain injury
title_full Mixed acid-base disorder secondary to topiramate use in traumatic brain injury
title_fullStr Mixed acid-base disorder secondary to topiramate use in traumatic brain injury
title_full_unstemmed Mixed acid-base disorder secondary to topiramate use in traumatic brain injury
title_short Mixed acid-base disorder secondary to topiramate use in traumatic brain injury
title_sort mixed acid-base disorder secondary to topiramate use in traumatic brain injury
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131386/
https://www.ncbi.nlm.nih.gov/pubmed/27942179
http://dx.doi.org/10.4103/0971-4065.177136
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AT anandhu mixedacidbasedisordersecondarytotopiramateuseintraumaticbraininjury
AT balasubramaniama mixedacidbasedisordersecondarytotopiramateuseintraumaticbraininjury

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