An interesting case of renal amyloidosis

In amyloidosis, there is an extracellular deposition of beta-sheet fibrils. Over 25 proteins have been demonstrated to form amyloid. One of them is Ig amyloid light (AL) chains. We are presenting a 40-year-old female who presented with progressive kyphoscoliosis for last 2 years following a minor tr...

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Detalles Bibliográficos
Autores principales: Hajra, A., Bandyopadhyay, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131391/
https://www.ncbi.nlm.nih.gov/pubmed/27942184
http://dx.doi.org/10.4103/0971-4065.177143
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author Hajra, A.
Bandyopadhyay, D.
author_facet Hajra, A.
Bandyopadhyay, D.
author_sort Hajra, A.
collection PubMed
description In amyloidosis, there is an extracellular deposition of beta-sheet fibrils. Over 25 proteins have been demonstrated to form amyloid. One of them is Ig amyloid light (AL) chains. We are presenting a 40-year-old female who presented with progressive kyphoscoliosis for last 2 years following a minor trauma and bilateral pedal edema for last 3 months. On further investigation, we found that she had a biclonal variety of MM with amyloidosis of kidney leading to massive proteinuria. Very few case reports are available where patient with biclonal variety of MM develop renal amyloidosis.
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spelling pubmed-51313912016-12-09 An interesting case of renal amyloidosis Hajra, A. Bandyopadhyay, D. Indian J Nephrol Case Report In amyloidosis, there is an extracellular deposition of beta-sheet fibrils. Over 25 proteins have been demonstrated to form amyloid. One of them is Ig amyloid light (AL) chains. We are presenting a 40-year-old female who presented with progressive kyphoscoliosis for last 2 years following a minor trauma and bilateral pedal edema for last 3 months. On further investigation, we found that she had a biclonal variety of MM with amyloidosis of kidney leading to massive proteinuria. Very few case reports are available where patient with biclonal variety of MM develop renal amyloidosis. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC5131391/ /pubmed/27942184 http://dx.doi.org/10.4103/0971-4065.177143 Text en Copyright: © Indian Journal of Nephrology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Hajra, A.
Bandyopadhyay, D.
An interesting case of renal amyloidosis
title An interesting case of renal amyloidosis
title_full An interesting case of renal amyloidosis
title_fullStr An interesting case of renal amyloidosis
title_full_unstemmed An interesting case of renal amyloidosis
title_short An interesting case of renal amyloidosis
title_sort interesting case of renal amyloidosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131391/
https://www.ncbi.nlm.nih.gov/pubmed/27942184
http://dx.doi.org/10.4103/0971-4065.177143
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