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Carrion’s disease: an eradicable illness?

Carrion’s disease is a neglected tropical disease caused by Bartonella bacilliformis, a vector-borne pathogen restricted to the Andean valleys of Peru, Ecuador and Colombia. Carrion’s disease is a biphasic illness; in the acute phase the case-fatality rate can be as high as 88 %, related to high par...

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Autores principales: Gomes, Cláudia, Pons, Maria J., del Valle Mendoza, Juana, Ruiz, Joaquim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131403/
https://www.ncbi.nlm.nih.gov/pubmed/27903286
http://dx.doi.org/10.1186/s40249-016-0197-7
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author Gomes, Cláudia
Pons, Maria J.
del Valle Mendoza, Juana
Ruiz, Joaquim
author_facet Gomes, Cláudia
Pons, Maria J.
del Valle Mendoza, Juana
Ruiz, Joaquim
author_sort Gomes, Cláudia
collection PubMed
description Carrion’s disease is a neglected tropical disease caused by Bartonella bacilliformis, a vector-borne pathogen restricted to the Andean valleys of Peru, Ecuador and Colombia. Carrion’s disease is a biphasic illness; in the acute phase the case-fatality rate can be as high as 88 %, related to high parasitemia, arriving to almost all erythrocytes, and secondary bacterial infections close related with the development of transient immunosuppression in the earlier illness phases. In addition, there are an undefined number of asymptomatic carriers that are reservoirs of the etiological agent of Carrion’s disease in endemic areas, they make take into account due to they are the perpetuators of this disease. The actual scenario of Carrion’s disease, in which the illness is arriving to new areas, due to the expansion of the vector’s distribution, suggests that now may be a crucial time to design a strategy focusing on its elimination. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s40249-016-0197-7) contains supplementary material, which is available to authorized users.
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spelling pubmed-51314032016-12-12 Carrion’s disease: an eradicable illness? Gomes, Cláudia Pons, Maria J. del Valle Mendoza, Juana Ruiz, Joaquim Infect Dis Poverty Commentary Carrion’s disease is a neglected tropical disease caused by Bartonella bacilliformis, a vector-borne pathogen restricted to the Andean valleys of Peru, Ecuador and Colombia. Carrion’s disease is a biphasic illness; in the acute phase the case-fatality rate can be as high as 88 %, related to high parasitemia, arriving to almost all erythrocytes, and secondary bacterial infections close related with the development of transient immunosuppression in the earlier illness phases. In addition, there are an undefined number of asymptomatic carriers that are reservoirs of the etiological agent of Carrion’s disease in endemic areas, they make take into account due to they are the perpetuators of this disease. The actual scenario of Carrion’s disease, in which the illness is arriving to new areas, due to the expansion of the vector’s distribution, suggests that now may be a crucial time to design a strategy focusing on its elimination. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s40249-016-0197-7) contains supplementary material, which is available to authorized users. BioMed Central 2016-12-01 /pmc/articles/PMC5131403/ /pubmed/27903286 http://dx.doi.org/10.1186/s40249-016-0197-7 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Commentary
Gomes, Cláudia
Pons, Maria J.
del Valle Mendoza, Juana
Ruiz, Joaquim
Carrion’s disease: an eradicable illness?
title Carrion’s disease: an eradicable illness?
title_full Carrion’s disease: an eradicable illness?
title_fullStr Carrion’s disease: an eradicable illness?
title_full_unstemmed Carrion’s disease: an eradicable illness?
title_short Carrion’s disease: an eradicable illness?
title_sort carrion’s disease: an eradicable illness?
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131403/
https://www.ncbi.nlm.nih.gov/pubmed/27903286
http://dx.doi.org/10.1186/s40249-016-0197-7
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