Prognostic biomarkers to identify patients destined to develop severe Crohn’s disease who may benefit from early biological therapy: protocol for a systematic review, meta-analysis and external validation

BACKGROUND: It is believed increasingly that patients with severe Crohn’s disease are best treated early with biological therapy, which may ameliorate subsequent disease course and diminish long-term complications. However, we cannot predict currently which new presentations of Crohn’s disease are d...

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Detalles Bibliográficos
Autores principales: Halligan, Steve, Boone, Darren, Bhatnagar, Gauraang, Ahmad, Tariq, Bloom, Stuart, Rodriguez-Justo, Manuel, Taylor, Stuart A., Mallett, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131410/
https://www.ncbi.nlm.nih.gov/pubmed/27903285
http://dx.doi.org/10.1186/s13643-016-0383-5

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