Differential humoral and cellular immunity induced by vaccination using plasmid DNA and protein recombinant expressing the NS3 protein of dengue virus type 3

BACKGROUND: The dengue non-structural 3 (NS3) is a multifunctional protein, containing a serine-protease domain, located at the N-terminal portion, and helicase, NTPase and RTPase domains present in the C-terminal region. This protein is considered the main target for CD4+ and CD8+ T cell responses...

Descripción completa

Detalles Bibliográficos
Autores principales: Hurtado-Melgoza, M. L., Ramos-Ligonio, A., Álvarez-Rodríguez, L. M., Meza-Menchaca, T., López-Monteon, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131448/
https://www.ncbi.nlm.nih.gov/pubmed/27903271
http://dx.doi.org/10.1186/s12929-016-0302-z

Ejemplares similares

Ejemplares similares