Systematic analysis of chromatin interactions at disease associated loci links novel candidate genes to inflammatory bowel disease

BACKGROUND: Genome-wide association studies (GWAS) have revealed many susceptibility loci for complex genetic diseases. For most loci, the causal genes have not been identified. Currently, the identification of candidate genes is predominantly based on genes that localize close to or within identifi...

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Detalles Bibliográficos
Autores principales: Meddens, Claartje A., Harakalova, Magdalena, van den Dungen, Noortje A. M., Foroughi Asl, Hassan, Hijma, Hemme J., Cuppen, Edwin P. J. G., Björkegren, Johan L. M., Asselbergs, Folkert W., Nieuwenhuis, Edward E. S., Mokry, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131449/
https://www.ncbi.nlm.nih.gov/pubmed/27903283
http://dx.doi.org/10.1186/s13059-016-1100-3

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