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Inhibition of bromodomain and extra-terminal (BET) proteins increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells: role of cMYC-IRF4-miR-125b interplay

BACKGROUND: Anti-cancer immune responses may contribute to the control of tumors after conventional chemotherapy, and different observations have indicated that chemotherapeutic agents can induce immune responses resulting in cancer cell death and immune-stimulatory side effects. Increasing experime...

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Detalles Bibliográficos
Autores principales: Abruzzese, Maria Pia, Bilotta, Maria Teresa, Fionda, Cinzia, Zingoni, Alessandra, Soriani, Alessandra, Vulpis, Elisabetta, Borrelli, Cristiana, Zitti, Beatrice, Petrucci, Maria Teresa, Ricciardi, Maria Rosaria, Molfetta, Rosa, Paolini, Rossella, Santoni, Angela, Cippitelli, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131470/
https://www.ncbi.nlm.nih.gov/pubmed/27903272
http://dx.doi.org/10.1186/s13045-016-0362-2