Pesticide toxicogenomics across scales: in vitro transcriptome predicts mechanisms and outcomes of exposure in vivo

In vitro Omics analysis (i.e. transcriptome) is suggested to predict in vivo toxicity and adverse effects in humans, although the causal link between high-throughput data and effects in vivo is not easily established. Indeed, the chemical-organism interaction can involve processes, such as adaptatio...

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Detalles Bibliográficos
Autores principales: Porreca, Immacolata, D’Angelo, Fulvio, De Franceschi, Lucia, Mattè, Alessandro, Ceccarelli, Michele, Iolascon, Achille, Zamò, Alberto, Russo, Filomena, Ravo, Maria, Tarallo, Roberta, Scarfò, Marzia, Weisz, Alessandro, De Felice, Mario, Mallardo, Massimo, Ambrosino, Concetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131489/
https://www.ncbi.nlm.nih.gov/pubmed/27905518
http://dx.doi.org/10.1038/srep38131

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