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In vitro and in vivo anti-malarial activity of novel harmine-analog heat shock protein 90 inhibitors: a possible partner for artemisinin

BACKGROUND: The emergence of artemisinin-resistant Plasmodium falciparum strains poses a serious challenge to the control of malaria. This necessitates the development of new anti-malarial drugs. Previous studies have shown that the natural beta-carboline alkaloid harmine is a promising anti-malaria...

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Detalles Bibliográficos
Autores principales:	Bayih, Abebe Genetu, Folefoc, Asongna, Mohon, Abu Naser, Eagon, Scott, Anderson, Marc, Pillai, Dylan R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131496/ https://www.ncbi.nlm.nih.gov/pubmed/27903279 http://dx.doi.org/10.1186/s12936-016-1625-7

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