Cysteinyl Leukotrienes Pathway Genes, Atopic Asthma and Drug Response: From Population Isolates to Large Genome-Wide Association Studies

Genetic variants associated with asthma pathogenesis and altered response to drug therapy are discussed. Many studies implicate polymorphisms in genes encoding the enzymes responsible for leukotriene synthesis and intracellular signaling through activation of seven transmembrane domain receptors, su...

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Detalles Bibliográficos
Autores principales: Thompson, Miles D., Capra, Valerie, Clunes, Mark T., Rovati, G. E., Stankova, Jana, Maj, Mary C., Duffy, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131607/
https://www.ncbi.nlm.nih.gov/pubmed/27990118
http://dx.doi.org/10.3389/fphar.2016.00299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131607/
https://www.ncbi.nlm.nih.gov/pubmed/27990118
http://dx.doi.org/10.3389/fphar.2016.00299

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