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Studying the role of cooperative hydration in stabilizing folded protein states

Understanding and modelling protein folding remains a key scientific and engineering challenge. Two key questions in protein folding are (1) why many proteins adopt a folded state and (2) how these proteins transition from the random coil ensemble to a folded state. In this paper we employ molecular...

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Detalles Bibliográficos
Autor principal: Huggins, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131609/
https://www.ncbi.nlm.nih.gov/pubmed/27633532
http://dx.doi.org/10.1016/j.jsb.2016.09.003