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Metabolic ketoacidosis with normal blood glucose: A rare complication of sodium–glucose cotransporter 2 inhibitors

Ketoacidosis is a significant and often a life-threatening complication of diabetes mellitus seen mostly in type 1 diabetes mellitus as well as occasionally in type 2 diabetes mellitus. Diabetic ketoacidosis usually manifests with high blood glucose more than 250 mg/dL, but euglycemic diabetic ketoa...

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Detalles Bibliográficos
Autores principales: Ullah, Saad, Khan, Noman, Zeb, Hassan, Tahir, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131811/
https://www.ncbi.nlm.nih.gov/pubmed/27928503
http://dx.doi.org/10.1177/2050313X16675259
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author Ullah, Saad
Khan, Noman
Zeb, Hassan
Tahir, Hassan
author_facet Ullah, Saad
Khan, Noman
Zeb, Hassan
Tahir, Hassan
author_sort Ullah, Saad
collection PubMed
description Ketoacidosis is a significant and often a life-threatening complication of diabetes mellitus seen mostly in type 1 diabetes mellitus as well as occasionally in type 2 diabetes mellitus. Diabetic ketoacidosis usually manifests with high blood glucose more than 250 mg/dL, but euglycemic diabetic ketoacidosis is defined as ketoacidosis associated with blood glucose level less than 250 mg/dL. Normal blood glucose in such patients results in significant delay in diagnosis and management of diabetic ketoacidosis, thus increasing mortality and morbidity. We present a case of euglycemic diabetic ketoacidosis secondary to canagliflozin in a type 2 diabetic patient.
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spelling pubmed-51318112016-12-07 Metabolic ketoacidosis with normal blood glucose: A rare complication of sodium–glucose cotransporter 2 inhibitors Ullah, Saad Khan, Noman Zeb, Hassan Tahir, Hassan SAGE Open Med Case Rep Case Report Ketoacidosis is a significant and often a life-threatening complication of diabetes mellitus seen mostly in type 1 diabetes mellitus as well as occasionally in type 2 diabetes mellitus. Diabetic ketoacidosis usually manifests with high blood glucose more than 250 mg/dL, but euglycemic diabetic ketoacidosis is defined as ketoacidosis associated with blood glucose level less than 250 mg/dL. Normal blood glucose in such patients results in significant delay in diagnosis and management of diabetic ketoacidosis, thus increasing mortality and morbidity. We present a case of euglycemic diabetic ketoacidosis secondary to canagliflozin in a type 2 diabetic patient. SAGE Publications 2016-11-24 /pmc/articles/PMC5131811/ /pubmed/27928503 http://dx.doi.org/10.1177/2050313X16675259 Text en © The Author(s) 2016 http://creativecommons.org/licenses/by-nc/3.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Ullah, Saad
Khan, Noman
Zeb, Hassan
Tahir, Hassan
Metabolic ketoacidosis with normal blood glucose: A rare complication of sodium–glucose cotransporter 2 inhibitors
title Metabolic ketoacidosis with normal blood glucose: A rare complication of sodium–glucose cotransporter 2 inhibitors
title_full Metabolic ketoacidosis with normal blood glucose: A rare complication of sodium–glucose cotransporter 2 inhibitors
title_fullStr Metabolic ketoacidosis with normal blood glucose: A rare complication of sodium–glucose cotransporter 2 inhibitors
title_full_unstemmed Metabolic ketoacidosis with normal blood glucose: A rare complication of sodium–glucose cotransporter 2 inhibitors
title_short Metabolic ketoacidosis with normal blood glucose: A rare complication of sodium–glucose cotransporter 2 inhibitors
title_sort metabolic ketoacidosis with normal blood glucose: a rare complication of sodium–glucose cotransporter 2 inhibitors
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131811/
https://www.ncbi.nlm.nih.gov/pubmed/27928503
http://dx.doi.org/10.1177/2050313X16675259
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