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Consistent sex-dependent effects of PKMζ gene ablation and pharmacological inhibition on the maintenance of referred pain
BACKGROUND: Persistently active PKMζ has been implicated in maintaining spinal nociceptive sensitization that underlies pain hypersensitivity. However, evidence for PKMζ in the maintenance of pain hypersensitivity comes exclusively from short-term studies in males using pharmacological agents of que...
Autores principales: | Nasir, Hibatulnaseer, Mahboubi, Hicham, Gyawali, Sandeep, Ding, Stephanie, Mickeviciute, Aiste, Ragavendran, J Vaigunda, Laferrière, André, Stochaj, Ursula, Coderre, Terence J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131814/ https://www.ncbi.nlm.nih.gov/pubmed/27899695 http://dx.doi.org/10.1177/1744806916675347 |
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