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Consistent sex-dependent effects of PKMζ gene ablation and pharmacological inhibition on the maintenance of referred pain

BACKGROUND: Persistently active PKMζ has been implicated in maintaining spinal nociceptive sensitization that underlies pain hypersensitivity. However, evidence for PKMζ in the maintenance of pain hypersensitivity comes exclusively from short-term studies in males using pharmacological agents of que...

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Detalles Bibliográficos
Autores principales: Nasir, Hibatulnaseer, Mahboubi, Hicham, Gyawali, Sandeep, Ding, Stephanie, Mickeviciute, Aiste, Ragavendran, J Vaigunda, Laferrière, André, Stochaj, Ursula, Coderre, Terence J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131814/
https://www.ncbi.nlm.nih.gov/pubmed/27899695
http://dx.doi.org/10.1177/1744806916675347

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