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High-throughput allele-specific expression across 250 environmental conditions

Gene-by-environment (GxE) interactions determine common disease risk factors and biomedically relevant complex traits. However, quantifying how the environment modulates genetic effects on human quantitative phenotypes presents unique challenges. Environmental covariates are complex and difficult to...

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Detalles Bibliográficos
Autores principales: Moyerbrailean, Gregory A., Richards, Allison L., Kurtz, Daniel, Kalita, Cynthia A., Davis, Gordon O., Harvey, Chris T., Alazizi, Adnan, Watza, Donovan, Sorokin, Yoram, Hauff, Nancy, Zhou, Xiang, Wen, Xiaoquan, Pique-Regi, Roger, Luca, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131815/
https://www.ncbi.nlm.nih.gov/pubmed/27934696
http://dx.doi.org/10.1101/gr.209759.116