Whole-genome analysis of the methylome and hydroxymethylome in normal and malignant lung and liver

DNA methylation at the 5-position of cytosine (5mC) is an epigenetic modification that regulates gene expression and cellular plasticity in development and disease. The ten-eleven translocation (TET) gene family oxidizes 5mC to 5-hydroxymethylcytosine (5hmC), providing an active mechanism for DNA de...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xin, Liu, Yun, Salz, Tal, Hansen, Kasper D., Feinberg, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131824/
https://www.ncbi.nlm.nih.gov/pubmed/27737935
http://dx.doi.org/10.1101/gr.211854.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131824/
https://www.ncbi.nlm.nih.gov/pubmed/27737935
http://dx.doi.org/10.1101/gr.211854.116

Ejemplares similares