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Whole-genome analysis of the methylome and hydroxymethylome in normal and malignant lung and liver

DNA methylation at the 5-position of cytosine (5mC) is an epigenetic modification that regulates gene expression and cellular plasticity in development and disease. The ten-eleven translocation (TET) gene family oxidizes 5mC to 5-hydroxymethylcytosine (5hmC), providing an active mechanism for DNA de...

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Detalles Bibliográficos
Autores principales:	Li, Xin, Liu, Yun, Salz, Tal, Hansen, Kasper D., Feinberg, Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2016
Materias:	Resource
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131824/ https://www.ncbi.nlm.nih.gov/pubmed/27737935 http://dx.doi.org/10.1101/gr.211854.116

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