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Ultradian glucocorticoid exposure directs gene-dependent and tissue-specific mRNA expression patterns in vivo

In this paper we report differential decoding of the ultradian corticosterone signal by glucocorticoid target tissues. Pulsatile corticosterone replacement in adrenalectomised rats resulted in different dynamics of Sgk1 mRNA production, with a distinct pulsatile mRNA induction profile observed in th...

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Detalles Bibliográficos
Autores principales: George, Charlotte L., Birnie, Matthew T., Flynn, Benjamin P., Kershaw, Yvonne M., Lightman, Stafford L., Conway-Campbell, Becky L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: North Holland Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131830/
https://www.ncbi.nlm.nih.gov/pubmed/27769714
http://dx.doi.org/10.1016/j.mce.2016.10.019