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Ultradian glucocorticoid exposure directs gene-dependent and tissue-specific mRNA expression patterns in vivo
In this paper we report differential decoding of the ultradian corticosterone signal by glucocorticoid target tissues. Pulsatile corticosterone replacement in adrenalectomised rats resulted in different dynamics of Sgk1 mRNA production, with a distinct pulsatile mRNA induction profile observed in th...
Autores principales: | George, Charlotte L., Birnie, Matthew T., Flynn, Benjamin P., Kershaw, Yvonne M., Lightman, Stafford L., Conway-Campbell, Becky L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
North Holland Publishing
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131830/ https://www.ncbi.nlm.nih.gov/pubmed/27769714 http://dx.doi.org/10.1016/j.mce.2016.10.019 |
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