Vaccinia Virus Protein C6 Inhibits Type I IFN Signalling in the Nucleus and Binds to the Transactivation Domain of STAT2

The type I interferon (IFN) response is a crucial innate immune signalling pathway required for defense against viral infection. Accordingly, the great majority of mammalian viruses possess means to inhibit this important host immune response. Here we show that vaccinia virus (VACV) strain Western R...

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Detalles Bibliográficos
Autores principales: Stuart, Jennifer H., Sumner, Rebecca P., Lu, Yongxu, Snowden, Joseph S., Smith, Geoffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131898/
https://www.ncbi.nlm.nih.gov/pubmed/27907166
http://dx.doi.org/10.1371/journal.ppat.1005955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131898/
https://www.ncbi.nlm.nih.gov/pubmed/27907166
http://dx.doi.org/10.1371/journal.ppat.1005955

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