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CD8(+) T Cells Induce Fatal Brainstem Pathology during Cerebral Malaria via Luminal Antigen-Specific Engagement of Brain Vasculature

Cerebral malaria (CM) is a severe complication of Plasmodium falciparum infection that results in thousands of deaths each year, mostly in African children. The in vivo mechanisms underlying this fatal condition are not entirely understood. Using the animal model of experimental cerebral malaria (EC...

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Detalles Bibliográficos
Autores principales: Swanson, Phillip A., Hart, Geoffrey T., Russo, Matthew V., Nayak, Debasis, Yazew, Takele, Peña, Mirna, Khan, Shahid M., Janse, Chris J., Pierce, Susan K., McGavern, Dorian B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131904/
https://www.ncbi.nlm.nih.gov/pubmed/27907215
http://dx.doi.org/10.1371/journal.ppat.1006022