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CD8(+) T Cells Induce Fatal Brainstem Pathology during Cerebral Malaria via Luminal Antigen-Specific Engagement of Brain Vasculature
Cerebral malaria (CM) is a severe complication of Plasmodium falciparum infection that results in thousands of deaths each year, mostly in African children. The in vivo mechanisms underlying this fatal condition are not entirely understood. Using the animal model of experimental cerebral malaria (EC...
Autores principales: | Swanson, Phillip A., Hart, Geoffrey T., Russo, Matthew V., Nayak, Debasis, Yazew, Takele, Peña, Mirna, Khan, Shahid M., Janse, Chris J., Pierce, Susan K., McGavern, Dorian B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131904/ https://www.ncbi.nlm.nih.gov/pubmed/27907215 http://dx.doi.org/10.1371/journal.ppat.1006022 |
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