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Intraluminal Flagellin Differentially Contributes to Gut Dysbiosis and Systemic Inflammation following Burn Injury
Burn injury is associated with a loss of gut barrier function, resulting in systemic dissemination of gut-derived bacteria and their products. The bacterial protein and TLR5 agonist, flagellin, induces non-specific innate immune responses. Because we detected flagellin in the serum of burn patients,...
Autores principales: | Grimes, Logan, Doyle, Allie, Miller, Aaron L., Pyles, Richard B., Olah, Gabor, Szabo, Csaba, Hoskins, Sarah, Eaves-Pyles, Tonyia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131931/ https://www.ncbi.nlm.nih.gov/pubmed/27907005 http://dx.doi.org/10.1371/journal.pone.0166770 |
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