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Intraluminal Flagellin Differentially Contributes to Gut Dysbiosis and Systemic Inflammation following Burn Injury

Burn injury is associated with a loss of gut barrier function, resulting in systemic dissemination of gut-derived bacteria and their products. The bacterial protein and TLR5 agonist, flagellin, induces non-specific innate immune responses. Because we detected flagellin in the serum of burn patients,...

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Detalles Bibliográficos
Autores principales: Grimes, Logan, Doyle, Allie, Miller, Aaron L., Pyles, Richard B., Olah, Gabor, Szabo, Csaba, Hoskins, Sarah, Eaves-Pyles, Tonyia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131931/
https://www.ncbi.nlm.nih.gov/pubmed/27907005
http://dx.doi.org/10.1371/journal.pone.0166770

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