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A Simplified and Efficient Process for Insulin Production in Pichia pastoris

A significant barrier to insulin is affordability. In this manuscript we describe improvements to key steps in the insulin production process in Pichia pastoris that reduce cost and time. The strategy for recovery and processing of human insulin precursor has been streamlined to two steps from biore...

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Detalles Bibliográficos
Autores principales:	Polez, Sulena, Origi, Domenico, Zahariev, Sotir, Guarnaccia, Corrado, Tisminetzky, Sergio G., Skoko, Nataša, Baralle, Marco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131935/ https://www.ncbi.nlm.nih.gov/pubmed/27907132 http://dx.doi.org/10.1371/journal.pone.0167207

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