Prediction of Impending Type 1 Diabetes through Automated Dual-Label Measurement of Proinsulin:C-Peptide Ratio

BACKGROUND: The hyperglycemic clamp test, the gold standard of beta cell function, predicts impending type 1 diabetes in islet autoantibody-positive individuals, but the latter may benefit from less invasive function tests such as the proinsulin:C-peptide ratio (PI:C). The present study aims to opti...

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Detalles Bibliográficos
Autores principales: Van Dalem, Annelien, Demeester, Simke, Balti, Eric V., Keymeulen, Bart, Gillard, Pieter, Lapauw, Bruno, De Block, Christophe, Abrams, Pascale, Weber, Eric, Vermeulen, Ilse, De Pauw, Pieter, Pipeleers, Daniël, Weets, Ilse, Gorus, Frans K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131964/
https://www.ncbi.nlm.nih.gov/pubmed/27907006
http://dx.doi.org/10.1371/journal.pone.0166702

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