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Role of Heterogeneous Macromolecular Crowding and Geometrical Irregularity at Central Excitatory Synapses in Shaping Synaptic Transmission

Besides the geometrical tortousity due to the extrasynaptic structures, macromolecular crowding and geometrical irregularities constituting the cleft composition at central excitatory synapses has a major and direct role in retarding the glutamate diffusion within the cleft space. However, the cleft...

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Detalles Bibliográficos
Autores principales: Gupta, Rahul, Reneaux, Melissa, Karmeshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131996/
https://www.ncbi.nlm.nih.gov/pubmed/27907112
http://dx.doi.org/10.1371/journal.pone.0167505