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Statistical Frailty Modeling for Quantitative Analysis of Exocytotic Events Recorded by Live Cell Imaging: Rapid Release of Insulin-Containing Granules Is Impaired in Human Diabetic β-cells

Hormones and neurotransmitters are released when secretory granules or synaptic vesicles fuse with the cell membrane, a process denoted exocytosis. Modern imaging techniques, in particular total internal reflection fluorescence (TIRF) microscopy, allow the investigator to monitor secretory granules...

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Detalles Bibliográficos
Autores principales:	Cortese, Giuliana, Gandasi, Nikhil R., Barg, Sebastian, Pedersen, Morten Gram
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132000/ https://www.ncbi.nlm.nih.gov/pubmed/27907065 http://dx.doi.org/10.1371/journal.pone.0167282

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