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Probing Functional Heteromeric Chemokine Protein–Protein Interactions through Conformation‐Assisted Oxime Ligation
Protein–protein interactions (PPIs) govern most processes in living cells. Current drug development strategies are aimed at disrupting or stabilizing PPIs, which require a thorough understanding of PPI mechanisms. Examples of such PPIs are heteromeric chemokine interactions that are potentially invo...
Autores principales: | Agten, Stijn M., Koenen, Rory R., Ippel, Hans, Eckardt, Veit, von Hundelshausen, Philipp, Mayo, Kevin H., Weber, Christian, Hackeng, Tilman M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132021/ https://www.ncbi.nlm.nih.gov/pubmed/27785869 http://dx.doi.org/10.1002/anie.201607036 |
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