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Machine Perfusion of Donor Livers for Transplantation: A Proposal for Standardized Nomenclature and Reporting Guidelines

With increasing demand for donor organs for transplantation, machine perfusion (MP) promises to be a beneficial alternative preservation method for donor livers, particularly those considered to be of suboptimal quality, also known as extended criteria donor livers. Over the last decade, numerous st...

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Autores principales: Karangwa, S. A., Dutkowski, P., Fontes, P., Friend, P. J., Guarrera, J. V., Markmann, J. F., Mergental, H., Minor, T., Quintini, C., Selzner, M., Uygun, K., Watson, C. J., Porte, R. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132023/
https://www.ncbi.nlm.nih.gov/pubmed/27129409
http://dx.doi.org/10.1111/ajt.13843
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author Karangwa, S. A.
Dutkowski, P.
Fontes, P.
Friend, P. J.
Guarrera, J. V.
Markmann, J. F.
Mergental, H.
Minor, T.
Quintini, C.
Selzner, M.
Uygun, K.
Watson, C. J.
Porte, R. J.
author_facet Karangwa, S. A.
Dutkowski, P.
Fontes, P.
Friend, P. J.
Guarrera, J. V.
Markmann, J. F.
Mergental, H.
Minor, T.
Quintini, C.
Selzner, M.
Uygun, K.
Watson, C. J.
Porte, R. J.
author_sort Karangwa, S. A.
collection PubMed
description With increasing demand for donor organs for transplantation, machine perfusion (MP) promises to be a beneficial alternative preservation method for donor livers, particularly those considered to be of suboptimal quality, also known as extended criteria donor livers. Over the last decade, numerous studies researching MP of donor livers have been published and incredible advances have been made in both experimental and clinical research in this area. With numerous research groups working on MP, various techniques are being explored, often applying different nomenclature. The objective of this review is to catalog the differences observed in the nomenclature used in the current literature to denote various MP techniques and the manner in which methodology is reported. From this analysis, we propose a standardization of nomenclature on liver MP to maximize consistency and to enable reliable comparison and meta‐analyses of studies. In addition, we propose a standardized set of guidelines for reporting the methodology of future studies on liver MP that will facilitate comparison as well as clinical implementation of liver MP procedures.
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spelling pubmed-51320232016-12-02 Machine Perfusion of Donor Livers for Transplantation: A Proposal for Standardized Nomenclature and Reporting Guidelines Karangwa, S. A. Dutkowski, P. Fontes, P. Friend, P. J. Guarrera, J. V. Markmann, J. F. Mergental, H. Minor, T. Quintini, C. Selzner, M. Uygun, K. Watson, C. J. Porte, R. J. Am J Transplant Original Articles With increasing demand for donor organs for transplantation, machine perfusion (MP) promises to be a beneficial alternative preservation method for donor livers, particularly those considered to be of suboptimal quality, also known as extended criteria donor livers. Over the last decade, numerous studies researching MP of donor livers have been published and incredible advances have been made in both experimental and clinical research in this area. With numerous research groups working on MP, various techniques are being explored, often applying different nomenclature. The objective of this review is to catalog the differences observed in the nomenclature used in the current literature to denote various MP techniques and the manner in which methodology is reported. From this analysis, we propose a standardization of nomenclature on liver MP to maximize consistency and to enable reliable comparison and meta‐analyses of studies. In addition, we propose a standardized set of guidelines for reporting the methodology of future studies on liver MP that will facilitate comparison as well as clinical implementation of liver MP procedures. John Wiley and Sons Inc. 2016-06-13 2016-10 /pmc/articles/PMC5132023/ /pubmed/27129409 http://dx.doi.org/10.1111/ajt.13843 Text en © 2016 The Authors. American Journal of Transplantation published by Wiley Periodicals, Inc. on behalf of American Society of Transplant Surgeons This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Articles
Karangwa, S. A.
Dutkowski, P.
Fontes, P.
Friend, P. J.
Guarrera, J. V.
Markmann, J. F.
Mergental, H.
Minor, T.
Quintini, C.
Selzner, M.
Uygun, K.
Watson, C. J.
Porte, R. J.
Machine Perfusion of Donor Livers for Transplantation: A Proposal for Standardized Nomenclature and Reporting Guidelines
title Machine Perfusion of Donor Livers for Transplantation: A Proposal for Standardized Nomenclature and Reporting Guidelines
title_full Machine Perfusion of Donor Livers for Transplantation: A Proposal for Standardized Nomenclature and Reporting Guidelines
title_fullStr Machine Perfusion of Donor Livers for Transplantation: A Proposal for Standardized Nomenclature and Reporting Guidelines
title_full_unstemmed Machine Perfusion of Donor Livers for Transplantation: A Proposal for Standardized Nomenclature and Reporting Guidelines
title_short Machine Perfusion of Donor Livers for Transplantation: A Proposal for Standardized Nomenclature and Reporting Guidelines
title_sort machine perfusion of donor livers for transplantation: a proposal for standardized nomenclature and reporting guidelines
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132023/
https://www.ncbi.nlm.nih.gov/pubmed/27129409
http://dx.doi.org/10.1111/ajt.13843
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