Cargando…

Pharmacokinetics and Safety of Defibrotide in Healthy Japanese Subjects

Detalles Bibliográficos
Autores principales:	Umemura, Kazuo, Iwaki, Takayuki, Kimura, Toshimi, Ogawa, Chitose, Fukuda, Takahiro, Taniguchi, Shuichi, Horibe, Keizo, Goto, Hiroaki, Yoshimura, Kenichi, Watanabe, Yasutaka, Nitani, Chika, Kikuta, Atsushi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Brief Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132046/ https://www.ncbi.nlm.nih.gov/pubmed/27870480 http://dx.doi.org/10.1002/cpdd.262

Ejemplares similares

The Pharmacokinetics and Pharmacodynamics of Prasugrel and Clopidogrel in Healthy Japanese Volunteers
por: Umemura, Kazuo, et al.
Publicado: (2016)

Pharmacokinetic profile of defibrotide in patients with renal impairment
por: Tocchetti, Paola, et al.
Publicado: (2016)

Development of a population pharmacokinetics and pharmacodynamics model of glucarpidase rescue treatment after high-dose methotrexate therapy
por: Fukaya, Yutaka, et al.
Publicado: (2023)

A Dose‐Confirmation Phase 1 Study to Evaluate the Safety and Pharmacology of Glucarpidase in Healthy Volunteers
por: Fukaya, Yutaka, et al.
Publicado: (2021)

Defibrotide for hepatic veno-occlusive disease
Publicado: (2021)

Defibrotide in the treatment of hepatic veno-occlusive disease
por: Fulgenzi, Alessandro, et al.
Publicado: (2016)

Defibrotide Therapy for SARS-CoV-2 ARDS
por: Frame, David, et al.
Publicado: (2022)

Defibrotide Has a Role in COVID-19 Therapy
por: Macciò, Antonio, et al.
Publicado: (2022)

Endothelium-protective, histone-neutralizing properties of the polyanionic agent defibrotide
por: Shi, Hui, et al.
Publicado: (2021)

[(18)F]FDG Uptake in the Aortic Wall Smooth Muscle of Atherosclerotic Plaques in the Simian Atherosclerosis Model
por: Iwaki, Takayuki, et al.
Publicado: (2016)

Up‐regulation of HDACs, a harbinger of uraemic endothelial dysfunction, is prevented by defibrotide
por: Palomo, Marta, et al.
Publicado: (2019)

Defibrotide Therapy for Sars CoV2 Acute Respiratory Distress Syndrome
por: Yanik, Gregory A, et al.
Publicado: (2021)

Influence of creatinine levels on survival in patients with veno-occlusive disease treated with defibrotide
por: Kong, Seom Gim, et al.
Publicado: (2022)

Defibrotide improved the outcome of monocrotaline induced rat hepatic sinusoidal obstruction syndrome
por: Liu, Zhenli, et al.
Publicado: (2022)

Characterization of Atherosclerosis Formation in a Murine Model of Type IIa Human Familial Hypercholesterolemia
por: Miyajima, Chiharu, et al.
Publicado: (2018)

Acute Graft-vs.-Host Disease-Associated Endothelial Activation in vitro Is Prevented by Defibrotide
por: Martinez-Sanchez, Julia, et al.
Publicado: (2019)

Pre-Exposure to Defibrotide Prevents Endothelial Cell Activation by Lipopolysaccharide: An Ingenuity Pathway Analysis
por: Orlando, Nicoletta, et al.
Publicado: (2020)

The importance of endothelial protection: the emerging role of defibrotide in reversing endothelial injury and its sequelae
por: Richardson, Paul G., et al.
Publicado: (2021)

Invariant nature of substituted element in metal-hexacyanoferrate
por: Niwa, Hideharu, et al.
Publicado: (2017)

Defibrotide (Defitelio): A New Addition to the Stockpile of Food and Drug Administration-approved Oligonucleotide Drugs
por: Stein, Cy, et al.
Publicado: (2016)

Defibrotide impact on the acute GVHD disease incidence in pediatric hematopoietic stem cell transplant recipients
por: Squillaci, Domenica, et al.
Publicado: (2023)

Defibrotide enhances fibrinolysis in human endotoxemia – a randomized, double blind, crossover trial in healthy volunteers
por: Schoergenhofer, Christian, et al.
Publicado: (2019)

Defibrotide inhibits donor leucocyte‐endothelial interactions and protects against acute graft‐versus‐host disease
por: García‐Bernal, David, et al.
Publicado: (2020)

Systematic review of defibrotide studies in the treatment of veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS)
por: Richardson, Paul, et al.
Publicado: (2019)

Use of Defibrotide in Patients with COVID-19 Pneumonia; Results of the Defi-VID19 Phase 2 Trial
por: Ruggeri, Annalisa, et al.
Publicado: (2021)

Real-world use of defibrotide for veno-occlusive disease/sinusoidal obstruction syndrome: the DEFIFrance Registry Study
por: Mohty, Mohamad, et al.
Publicado: (2022)

Defibrotide mitigates endothelial cell injury induced by plasmas from patients with COVID-19 and related vasculopathies
por: Elhadad, Sonia, et al.
Publicado: (2023)

A phase 2 trial of defibrotide for the prevention of chimeric antigen receptor T-cell–associated neurotoxicity syndrome
por: Jacobson, Caron A., et al.
Publicado: (2023)

Phase I clinical study of oral olaparib in pediatric patients with refractory solid tumors: study protocol
por: Takagi, Masatoshi, et al.
Publicado: (2019)

Proper cytoskeletal architecture beneath the plasma membrane of red blood cells requires Ttll4
por: Ijaz, Faryal, et al.
Publicado: (2017)

Endothelial dysfunction and its critical role in COVID‐19‐associated coagulopathy: Defibrotide as an endothelium‐protective, targeted therapy
por: García‐Bernal, David, et al.
Publicado: (2021)

Defibrotide: real-world management of veno-occlusive disease/sinusoidal obstructive syndrome after stem cell transplant
por: Nauffal, Mary, et al.
Publicado: (2022)

A Systematic Review and Meta-Analysis of Studies of Defibrotide Prophylaxis for Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome
por: Corbacioglu, Selim, et al.
Publicado: (2022)

Defibrotide Prophylaxis of Sinusoidal Obstruction Syndrome in Adults Treated With Inotuzumab Ozogamicin Prior to Hematopoietic Stem Cell Transplantation
por: Giglio, Fabio, et al.
Publicado: (2022)

Reliability of joint position sense measured in the knee using the level function of the iPhone “Measure” application
por: Nakashima, Yuki, et al.
Publicado: (2021)

Coexistence of Spontaneous Coronary Artery Dissection, Takotsubo Cardiomyopathy, and Myocardial Bridge
por: Kegai, Shuichi, et al.
Publicado: (2021)

A case report of severe veno-occlusive disease following autologous stem cell transplantation successfully treated with Defibrotide
por: Bahoush, Golamreza, et al.
Publicado: (2020)

Publisher Correction: Systematic review of defibrotide studies in the treatment of veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS)
por: Richardson, Paul, et al.
Publicado: (2019)

Platelet Aggregation Inhibitory Effects and Pharmacokinetics of Prasugrel Used in Combination With Aspirin in Healthy Japanese Subjects
por: Umemura, Kazuo, et al.
Publicado: (2016)

Sorafenib treatment in children with relapsed and refractory neuroblastoma: an experience of four cases
por: Okada, Keiko, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_f2lfautgj0tbmei3jn7so96rgv