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The Signature of MicroRNA Dysregulation in Muscle Paralyzed by Spinal Cord Injury Includes Downregulation of MicroRNAs that Target Myostatin Signaling

Spinal cord injury (SCI) results in muscle atrophy, reduced force generation and an oxidative-to-glycolytic fiber type shift. The mechanisms responsible for these alterations remain incompletely understood. To gain new insights regarding mechanisms involved in deterioration of muscle after SCI, glob...

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Detalles Bibliográficos
Autores principales: De Gasperi, Rita, Graham, Zachary A., Harlow, Lauren M., Bauman, William A., Qin, Weiping, Cardozo, Christopher P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132212/
https://www.ncbi.nlm.nih.gov/pubmed/27907012
http://dx.doi.org/10.1371/journal.pone.0166189