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Effect of Glu12-His89 Interaction on Dynamic Structures in HIV-1 p17 Matrix Protein Elucidated by NMR

To test the existence of the salt bridge and stability of the HIV-1 p17 matrix protein, an E12A (mutated at helix 1) was established to abolish possible electrostatic interactions. The chemical shift perturbation from the comparison between wild type and E12A suggested the existence of an electrosta...

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Detalles Bibliográficos
Autores principales:	Konagaya, Yuta, Miyakawa, Rina, Sato, Masumi, Matsugami, Akimasa, Watanabe, Satoru, Hayashi, Fumiaki, Kigawa, Takanori, Nishimura, Chiaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5132258/ https://www.ncbi.nlm.nih.gov/pubmed/27907055 http://dx.doi.org/10.1371/journal.pone.0167176

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